Triglyceride-glucose related indices, cardiometabolic multimorbidity, and risk of incident osteoarthritis: A prospective cohort study in UK Biobank

Kai-Bo Sun, Yuan-Gang Wu, Yu-Huan Xiang, Meng-Ying Li, Yang Ding, Ling-Sheng Zhang, Yi Zeng, Hui-Qi Xie, Bin Shen · 2026

Read Triglyceride-glucose related indices, cardiometabolic multimorbidity, and risk of incident osteoarthritis: A prospective cohort study in UK Biobank by Kai-Bo Sun, Yuan-Gang Wu, Yu-Huan Xiang, Meng-Ying Li, Yang Ding, Ling-Sheng Zhang, Yi Zeng, Hui-Qi Xie, Bin Shen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13546427.txt.

Description

Kai-Bo Sun and co-authors link a blood sugar and fat index to osteoarthritis risk, in a 2026 study. The index joins triglycerides and glucose, and versions of it fold in body size measures. Metabolic dysfunction may feed joint wear, but routine markers to flag future risk are limited.

The UK Biobank study held more than two hundred fifty thousand adults with no joint disease at start. Over follow up, more than forty thousand developed hospital recorded osteoarthritis. The top quarter of the body size versions of the index carried about twice the risk of the bottom quarter. Links were also checked by burden of heart and metabolic disease.

Catalog record

CREATORKai-Bo Sun, Yuan-Gang Wu, Yu-Huan Xiang, Meng-Ying Li, Yang Ding, Ling-Sheng Zhang, Yi Zeng, Hui-Qi Xie, Bin Shen
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE56 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13546427

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