Fatty Acid Metabolic Reprogramming in Rheumatoid Arthritis: Integrating Inflammation, Resolution Failure, and Joint Destruction

Tingting Li, Guanghuan Li, Yuyao Yang, Liang Han, Pan Shen, Xin Ba, Weiji Lin, Jiahui Yan, Ruiyuan Zhang, Simin Ma, Shenghao Tu, Kai Qin · 2026

Read Fatty Acid Metabolic Reprogramming in Rheumatoid Arthritis: Integrating Inflammation, Resolution Failure, and Joint Destruction by Tingting Li, Guanghuan Li, Yuyao Yang, Liang Han, Pan Shen, Xin Ba, Weiji Lin, Jiahui Yan, Ruiyuan Zhang, Simin Ma, Shenghao Tu, Kai Qin (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13546046.txt.

Description

Li and coauthors review how fat use shifts in rheumatoid arthritis. The illness causes long joint swelling and slow joint damage. Immune attack explains much of it, but not all of it. Swelling that fails to resolve and bone loss stay partly unclear.

New proof links fat fuel shifts to those gaps, the team argues. Fat supply shapes cell walls, cell power, and stress in cells. Fat parts also form signals that drive or calm swelling. The review maps those links by cell type in joint tissue. Such maps may point to new drug routes past immune blocks alone.

Catalog record

CREATORTingting Li, Guanghuan Li, Yuyao Yang, Liang Han, Pan Shen, Xin Ba, Weiji Lin, Jiahui Yan, Ruiyuan Zhang, Simin Ma, Shenghao Tu, Kai Qin
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE98 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13546046

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