NONcNZO10/LtJ and TALLY‐HO/JngJ Mice as Novel Models of Diabetic Peripheral Neuropathy
Stéphanie A Eid, Andrew D Carter, Emily J Koubek, John M Hayes, Diana M Rigan, Chloe Kiriluk, Crystal M Pacut, Phillipe D O'Brien, Jihyun Park, Dae‐Gyu Jang, Eva L Feldman · 2026
Read NONcNZO10/LtJ and TALLY‐HO/JngJ Mice as Novel Models of Diabetic Peripheral Neuropathy by Stéphanie A Eid, Andrew D Carter, Emily J Koubek, John M Hayes, Diana M Rigan, Chloe Kiriluk, Crystal M Pacut, Phillipe D O'Brien, Jihyun Park, Dae‐Gyu Jang, Eva L Feldman (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13545661.txt.
Description
Stephanie Eid and co-authors vet two mouse strains as models of diabetic nerve damage. This damage, a grave side effect of type 2 diabetes, eats nerve fibers from the far ends inward. Drug wins in mice often fail in people, in part because lab models match human illness poorly. The two strains here carry many small gene effects, like most patients.
By six months of age, both strains grew obese with high blood sugar and nerve damage. Their mix of traits tracked human disease more closely than older models. A calorie cut diet then improved body health in one strain and restored large fiber function. Small fiber counts in skin, though, stayed low.
Catalog record
| CREATOR | Stéphanie A Eid, Andrew D Carter, Emily J Koubek, John M Hayes, Diana M Rigan, Chloe Kiriluk, Crystal M Pacut, Phillipe D O'Brien, Jihyun Park, Dae‐Gyu Jang, Eva L Feldman |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |