Diagnostic significance of cancer antigen 125/carcinoembryonic antigen ratio combined with IOTA-ADNEX model in discriminating between primary ovarian cancer and ovarian metastases
Yaoqin Wang, Qianyi Zhang, Shixin Huang, Ruoxuan Lin, Lina Tang, Wenting Xie · 2026
Read Diagnostic significance of cancer antigen 125/carcinoembryonic antigen ratio combined with IOTA-ADNEX model in discriminating between primary ovarian cancer and ovarian metastases by Yaoqin Wang, Qianyi Zhang, Shixin Huang, Ruoxuan Lin, Lina Tang, Wenting Xie (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13545635.txt.
Description
Yaoqin Wang and co-authors tested in 2026 how well two tools separate ovarian cancer that starts in the ovary from cancer that spreads there from elsewhere. That distinction changes treatment and outlook. One tool is the ADNEX ultrasound risk model, and the other is the ratio between two blood markers, CA125 and CEA. Records of patients with confirmed diagnoses of each type were compared.
Most metastases in the group came from the digestive tract, and about half were found at the same time as the original tumor. Each tool worked reasonably on its own, yet combining the marker ratio with the ultrasound model performed best, with an accuracy near 84 percent. The authors suggest the pairing could sharpen decisions made before surgery.
Catalog record
| CREATOR | Yaoqin Wang, Qianyi Zhang, Shixin Huang, Ruoxuan Lin, Lina Tang, Wenting Xie |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |