Magnetic resonance imaging R2* mapping for evaluating Ki-67 proliferation index and cytokeratin 19 expression in solitary iron-sparing hepatocellular carcinoma: a retrospective single-center study
Sue Cao, Chenyu Dong, Jie Zhang, Quanxi Li, Jianbo Xu, Ruomi Guo · 2026
Read Magnetic resonance imaging R2* mapping for evaluating Ki-67 proliferation index and cytokeratin 19 expression in solitary iron-sparing hepatocellular carcinoma: a retrospective single-center study by Sue Cao, Chenyu Dong, Jie Zhang, Quanxi Li, Jianbo Xu, Ruomi Guo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13545566.txt.
Description
Sue Cao and co-authors asked in 2026 whether an MRI measurement of iron in the liver and tumor could predict aggressive features in a certain type of liver cancer. They reviewed 80 patients with a single tumor that spared iron, all treated with surgery at one center between 2018 and 2025. Two markers of tumor behavior, the Ki-67 growth index and CK19 expression, were checked against imaging values and a blood marker.
High Ki-67 was more likely when the blood marker AFP was very high, while higher liver iron values pointed the other way. Combining both measures predicted a high growth index moderately well. For CK19, only the blood marker carried predictive weight, which limits what the scan adds.
Catalog record
| CREATOR | Sue Cao, Chenyu Dong, Jie Zhang, Quanxi Li, Jianbo Xu, Ruomi Guo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |