Identification and characterization of POSTN+ synovial progenitor cells in meniscus regeneration
Wanting Yan, Xiaojia Huang, Jingsong Wang, Wennan Xu, Haozhi Zhang, Jiahao Zhu, Shuyang Guo, Weiping Li, Wei Zhao, Zhengzheng Zhang · 2026
Read Identification and characterization of POSTN+ synovial progenitor cells in meniscus regeneration by Wanting Yan, Xiaojia Huang, Jingsong Wang, Wennan Xu, Haozhi Zhang, Jiahao Zhu, Shuyang Guo, Weiping Li, Wei Zhao, Zhengzheng Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13545393.txt.
Description
Ten researchers in China searched for the cells that help a torn knee meniscus heal, in work published in 2026. The meniscus is a pad of cartilage in the knee, and its inner part has no blood supply, so it heals poorly. The team wanted to find which cells move in after injury and what they turn into. They used human tissue samples and a rabbit model of injury.
Gene tests on single cells found a group of cells from the joint lining that make large amounts of a protein called periostin. After injury, these cells grew fast, moved to the wound, and later turned toward a cartilage-like state. A gene switch named TCF7L1 seemed to guide this shift. When the team placed these cells into injured knees in rabbits, healing improved, which marks them as a target for new care.
Catalog record
| CREATOR | Wanting Yan, Xiaojia Huang, Jingsong Wang, Wennan Xu, Haozhi Zhang, Jiahao Zhu, Shuyang Guo, Weiping Li, Wei Zhao, Zhengzheng Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 66 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |