Circadian and behavioral timing in MASLD: a systematic review of human observational studies
Arunkumar Subramanian, Raja Affendi Raja Ali, Gavin Stewart Dawe, Vetriselvan Subramaniyan · 2026
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Description
Arunkumar Subramanian and three co-authors review body clock timing and liver fat in a 2026 paper. The disease, now called MASLD, links fatty liver with metabolic trouble. Daily timing of sleep, light, food, and activity may steer it. The team gathered human observational studies on such timing exposures.
Twenty four evidence sources met their rules, plus two related cirrhosis studies. Shift work showed the most consistent links and the deepest follow up data. Being a night owl tied to having the disease, but less clearly to its advanced stages. Meal and sleep timing evidence was thinner and mixed. Pooling was impossible, so findings were told as a narrative. The review maps where timing research on liver fat stands.
Catalog record
| CREATOR | Arunkumar Subramanian, Raja Affendi Raja Ali, Gavin Stewart Dawe, Vetriselvan Subramaniyan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 96 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |