Establishment and validation of an ADP-ribosylation-related gene signature for prognostic prediction in lung adenocarcinoma
Xuan Luo · 2026
Read Establishment and validation of an ADP-ribosylation-related gene signature for prognostic prediction in lung adenocarcinoma by Xuan Luo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13545184.txt.
Description
Xuan Luo, in a 2026 study, built a survival prediction score for lung adenocarcinoma from genes linked to ADP-ribosylation, a chemical tagging process that helps control DNA repair and cell death. Luo compared tumor and normal gene data from a large cancer database, then narrowed the candidates through several layers of statistical selection. Five genes survived into the final risk model.
Patients with low scores showed more immune cells inside their tumors and a lower mutation burden than high-score patients. The two groups also differed in predicted sensitivity to several chemotherapy and targeted drugs. Lab tests singled out one gene, ARL6IP1, which helped lung cancer cells grow, move, and resist death.
Catalog record
| CREATOR | Xuan Luo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33510 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |