Effects of surgical resection on tissue autofluorescence lifetime signatures in head and neck cancer: implications for intraoperative tumor margin assessment
Farzad Fereidouni, Willy Ju, Sarah Rezapourdamanab, Dena Sayrafi, Mohamed Abul Hassan, Brent Weyers, Xiangnan Zhou, Julien Bec, Dorina Gui, Andrew Birkeland, Laura Marcu · 2026
Read Effects of surgical resection on tissue autofluorescence lifetime signatures in head and neck cancer: implications for intraoperative tumor margin assessment by Farzad Fereidouni, Willy Ju, Sarah Rezapourdamanab, Dena Sayrafi, Mohamed Abul Hassan, Brent Weyers, Xiangnan Zhou, Julien Bec, Dorina Gui, Andrew Birkeland, Laura Marcu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13544624.txt.
Description
Farzad Fereidouni and co-authors study a light-based tool for cancer surgery in a 2026 paper. Surgeons removing head and neck tumours must judge where cancer ends, yet checks during surgery are limited. A method called fluorescence lifetime imaging reads how long tissue glows after a flash, and cancer glows differently from healthy tissue.
The team measured tissue from 75 patients both in the body and after removal, at three sites in the throat area. Removal changed the glow patterns, but not in the same way everywhere. Contrast fell for tongue and tonsil samples after removal, while it improved for the tongue base. The authors warn that diagnostic rules must be trained separately for use during surgery and on removed tissue.
Catalog record
| CREATOR | Farzad Fereidouni, Willy Ju, Sarah Rezapourdamanab, Dena Sayrafi, Mohamed Abul Hassan, Brent Weyers, Xiangnan Zhou, Julien Bec, Dorina Gui, Andrew Birkeland, Laura Marcu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |