Advances in Drug Delivery Systems Utilizing Glycyrrhizic Acid and Its Aglycone Glycyrrhetinic Acid in Cancer Therapy
Shanshan Liu, Dongyan Guo, Huan Tian, Jiangxue Cheng, Yajun Shi, Xiaofei Zhang, Junbo Zou, Bingtao Zhai · 2026
Read Advances in Drug Delivery Systems Utilizing Glycyrrhizic Acid and Its Aglycone Glycyrrhetinic Acid in Cancer Therapy by Shanshan Liu, Dongyan Guo, Huan Tian, Jiangxue Cheng, Yajun Shi, Xiaofei Zhang, Junbo Zou, Bingtao Zhai (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13544371.txt.
Description
Shanshan Liu and co-authors review how two licorice compounds could carry cancer drugs to their targets. Glycyrrhizic acid and its partner glycyrrhetinic acid fight tumors a little on their own, sit kindly in the body, latch onto liver-cell receptors, and dissolve in both water and fat. Those traits make them tempting building blocks for delivery systems.
The review sorts their three jobs. As cargo partners, they ride in carriers beside drugs like cisplatin and paclitaxel, sharpening effect and softening side effects. As ligands stuck on a carrier's skin, they steer it to tumor receptors. As self-assembling material, they form drug carriers with no separate vehicle at all. Production scale, stability in the body, and missing long-term safety data still block the clinic.
Catalog record
| CREATOR | Shanshan Liu, Dongyan Guo, Huan Tian, Jiangxue Cheng, Yajun Shi, Xiaofei Zhang, Junbo Zou, Bingtao Zhai |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 161 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |