Photocontrolled nanosystem potentiates photo-chemoimmunotherapy against TNBC by integrating apoptosis/ferroptosis/ pyroptosis and STING activation
Pan Zhang, Minglun Liu, Lei Huang, Zijie Zhao, Qianqian Zhang, Yunhao Li, Yuncong Chen, Lili Liang · 2026
Read Photocontrolled nanosystem potentiates photo-chemoimmunotherapy against TNBC by integrating apoptosis/ferroptosis/ pyroptosis and STING activation by Pan Zhang, Minglun Liu, Lei Huang, Zijie Zhao, Qianqian Zhang, Yunhao Li, Yuncong Chen, Lili Liang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13543977.txt.
Description
Pan Zhang and co-authors build a light controlled nano system to attack a hard type of breast cancer. Their paper from 2026 deals with triple negative breast cancer, which resists drugs and hides from the immune system. Single treatments fail to break both of those walls.
The platform gathers in tumors, then reacts to the acid and chemical setting inside them plus a near infrared light from outside. That joint trigger frees the drug in a controlled way at the cell power plants. The system kills tumor cells by three death paths at once. It also wakes a cell alarm path that turns cold tumors hot, drawing in killer immune cells in a mouse test with tumors on both sides.
Catalog record
| CREATOR | Pan Zhang, Minglun Liu, Lei Huang, Zijie Zhao, Qianqian Zhang, Yunhao Li, Yuncong Chen, Lili Liang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 71 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |