Long-distance trail running induces functional iron deficiency driven by inflammation

Anna Katharina Tobiasch, Tobias Dünnwald, Paolo Emilio Adami, Frederic Garrandes, Stéphane Bermon, Luca Brunelli, Andrea Griesmacher, Christian Irsara, Anika Köck, Markus Seifert, Johannes Bösch, Dietmar Fries, Wolfgang Schobersberger, Günter Weiss · 2026

Read Long-distance trail running induces functional iron deficiency driven by inflammation by Anna Katharina Tobiasch, Tobias Dünnwald, Paolo Emilio Adami, Frederic Garrandes, Stéphane Bermon, Luca Brunelli, Andrea Griesmacher, Christian Irsara, Anika Köck, Markus Seifert, Johannes Bösch, Dietmar Fries, Wolfgang Schobersberger, Günter Weiss (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13543947.txt.

Description

Anna Tobiasch and co-authors show that a long mountain race can starve tissues of iron for a while. Iron fuels cell energy making, but the body locks it away when inflammation flares. Seven elite runners gave blood before and after a world title trail race in Austria. The course ran close to ninety kilometers with huge climbs.

After the race, alarm signals and the iron locking hormone both rose. Free iron in the blood fell, even as stored iron read high. Signs of burst red cells showed too. Gene readings in blood cells matched a state of iron want: more uptake, less storage. The authors warn that such swings may dent cell energy in hard training blocks.

Catalog record

CREATORAnna Katharina Tobiasch, Tobias Dünnwald, Paolo Emilio Adami, Frederic Garrandes, Stéphane Bermon, Luca Brunelli, Andrea Griesmacher, Christian Irsara, Anika Köck, Markus Seifert, Johannes Bösch, Dietmar Fries, Wolfgang Schobersberger, Günter Weiss
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13543947

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