Limitations of evaluating risks of all cancers combined in etiological epidemiology research

Julie E Goodman, Satori A Marchitti, Nicole S Olgun, David L Eaton · 2026

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Description

Julie Goodman and co-authors warn against lumping all cancers into one risk bucket in a 2026 essay. Each cancer type is its own disease with its own causes. Yet a major agency once judged a chemical a carcinogen from links with all cancers combined, with no steady link to any single type.

Such pooled links can be false alarms with no body-level sense, the authors argue. They can also drown out real links to rare types. Poor control of side factors makes the risk worse. The authors urge teams that report pooled results to flag them as first-pass hints. Those hints can seed new studies, but they should not carry claims about how a chemical acts in the body.

Catalog record

CREATORJulie E Goodman, Satori A Marchitti, Nicole S Olgun, David L Eaton
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE18 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13543875

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