Kidney biopsy in patients with small kidneys: diagnostic yield and treatment modification in a retrospective cohort study
Wen Wang, Xing Chen, Ruopei Wang, Lijing Yao, Lu Zhang · 2026
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Description
Wang and co-authors ask whether biopsying shrunken kidneys is worth the needle, in this 2026 study. Small kidney size has long counted against biopsy, on the belief that late damage teaches little and changes less. Evidence for that belief was thin.
The team reviewed over a thousand biopsies at one center; seventy-six patients had kidneys of nine centimeters or less. Their samples revealed a spread of causes, led by one common scarring disease at about forty-six percent. Treatment changed for two thirds of the small-kidney patients after the results. Follow-up showed falling protein leakage and steady kidney function. The authors say selected patients gain real value from the procedure.
Catalog record
| CREATOR | Wen Wang, Xing Chen, Ruopei Wang, Lijing Yao, Lu Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |