MRI radiomics and 90Y PET dosimetry for predicting hepatocellular carcinoma response after radioembolization

Wenyu Huang, Jie Ding, Hongzhen Yuan, Zhidong Li, Huai Li, Yinglang Zeng · 2026

Read MRI radiomics and 90Y PET dosimetry for predicting hepatocellular carcinoma response after radioembolization by Wenyu Huang, Jie Ding, Hongzhen Yuan, Zhidong Li, Huai Li, Yinglang Zeng (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13543647.txt.

Description

Wenyu Huang and colleagues published a 2026 study predicting which liver cancers will respond to yttrium-90 radioembolization, a treatment that lodges radioactive microspheres in the tumour's blood supply. Records covered fifty-seven patients with confirmed hepatocellular carcinoma who had contrast MRI scans before treatment and a PET scan within a day after it to measure the radiation dose actually absorbed. Response was judged at three months by standard tumour criteria.

Thirty-two patients responded, all partially. The average absorbed dose at twenty-four hours independently predicted response, with each dose increment nudging the odds upward. A combined model mixing clinical features with MRI radiomics, the measurable texture of the scan, reached seventy-nine percent accuracy and caught most responders. Dose delivered plus tumour appearance, the authors argue, can flag early who needs a different plan.

Catalog record

CREATORWenyu Huang, Jie Ding, Hongzhen Yuan, Zhidong Li, Huai Li, Yinglang Zeng
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34010
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13543647

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