Cardiovascular-liver-metabolic multimorbidity: preliminary insights into the associations with the triglyceride glucose index (TyG), its obesity-derived indices and their effects on long-term survival
Shiming He, Yanfeng Liu, Guotai Sheng, Guobo Xie, Wei Wang, Hengli Lai, Yang Zou, Chao Wang · 2026
Read Cardiovascular-liver-metabolic multimorbidity: preliminary insights into the associations with the triglyceride glucose index (TyG), its obesity-derived indices and their effects on long-term survival by Shiming He, Yanfeng Liu, Guotai Sheng, Guobo Xie, Wei Wang, Hengli Lai, Yang Zou, Chao Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13543626.txt.
Description
In a 2026 study, Shiming He and colleagues compared versions of the triglyceride-glucose index as markers of cardiovascular-liver-metabolic multimorbidity. The index is a blood-based estimate of insulin resistance, and the condition is the clustering of heart, liver, and metabolic diseases in one person. In a national sample of 20,235 adults, the plain index and versions blended with waist and body-shape measures were tested against the combined condition and against long-term death risk.
Every version rose with multimorbidity, and the obesity-blended versions performed best at identifying it, with accuracy scores above 0.83 for the waist-weight and visceral-fat variants. Having the combined condition also amplified the mortality risk carried by high index values. Machine-learning importance analysis echoed the same two leaders. A refined blood-and-body index, the authors suggest, could screen for this dangerous clustering more sharply than metabolic measures alone.
Catalog record
| CREATOR | Shiming He, Yanfeng Liu, Guotai Sheng, Guobo Xie, Wei Wang, Hengli Lai, Yang Zou, Chao Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 62556 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |