Enhanced odontoblast regeneration and anti-inflammatory effects of nanocurcumin-loaded BM-MSC-derived exosomes in an LPS-induced periodontitis rat model

Nehad M. Abd-elmonsif, Ahmed Morsy, Mona El Deeb · 2026

Read Enhanced odontoblast regeneration and anti-inflammatory effects of nanocurcumin-loaded BM-MSC-derived exosomes in an LPS-induced periodontitis rat model by Nehad M. Abd-elmonsif, Ahmed Morsy, Mona El Deeb (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13543616.txt.

Description

Nehad Abd-elmonsif, Ahmed Morsy, and Mona El Deeb tested in 2026 a stem cell packet treatment for gum disease damage in rats. Gum disease can destroy the tooth-forming cells called odontoblasts. Tiny packets shed by bone marrow stem cells are known to calm swelling and aid repair, and curcumin in nano form shares those traits. The team loaded the packets with curcumin and compared both versions.

Twenty-eight rats were split into healthy, sick, and two treated groups, with the disease triggered by a bacterial toxin. Plain packets improved cell layout, collagen growth, and a calming immune signal. Loaded packets did better still on every measure. The authors call the loaded packets a promising cell-free route to rebuild gum and pulp tissue.

Catalog record

CREATORNehad M. Abd-elmonsif, Ahmed Morsy, Mona El Deeb
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13543616

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