Evaluation of tumor-infiltrating lymphocytes across breast cancer stages at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia
Emiyamrew Getnet, Gashaw Adane, Ephrem Awoke Shiferaw, Tadele Ayelegn Nibret, Gebremariam Maru Yemru, Minyahl Kassye Mengstu, Abebe Birhanu, Afewerk Habtamu, Habtu Debash, Tadelo Wondmagegn, Mulualem Lemma · 2026
Read Evaluation of tumor-infiltrating lymphocytes across breast cancer stages at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia by Emiyamrew Getnet, Gashaw Adane, Ephrem Awoke Shiferaw, Tadele Ayelegn Nibret, Gebremariam Maru Yemru, Minyahl Kassye Mengstu, Abebe Birhanu, Afewerk Habtamu, Habtu Debash, Tadelo Wondmagegn, Mulualem Lemma (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13543470.txt.
Description
Emiyamrew Getnet and colleagues published a 2026 cross-sectional study measuring tumour-infiltrating lymphocytes, immune cells found inside breast tumours, across cancer stages at Gondar's university hospital in northwest Ethiopia. Such scores predict outcomes elsewhere, but Ethiopian data were scarce. Sixty-two patients treated in a one-year window had stored tumour tissue stained and scored by international working-group rules, then compared with stage, grade, and nodal spread.
The pattern defied a simple good-news story: immune infiltration was lowest in stage II disease and highest in stage IV. Median scores reached about forty-eight percent in stage IV against seven percent in stage II, and higher grade tumours also carried more lymphocytes. Scores rose in step with overall stage, nodal stage, and grade. Advanced tumours may be more visible to the immune system, the authors suggest, and call for work linking the scores to molecular subtypes.
Catalog record
| CREATOR | Emiyamrew Getnet, Gashaw Adane, Ephrem Awoke Shiferaw, Tadele Ayelegn Nibret, Gebremariam Maru Yemru, Minyahl Kassye Mengstu, Abebe Birhanu, Afewerk Habtamu, Habtu Debash, Tadelo Wondmagegn, Mulualem Lemma |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31374 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |