Exercise training is associated with changes in adipocyte size and lipid metabolism in older women: cross-sectional and longitudinal study

Marek Wilhelm, Terezie Čížková, Klára Daďová, Michal Koc, Jana Neubert, Ondřej Kuda, Jan Gojda, Lenka Rossmeislová, Michaela Šiklová · 2026

Read Exercise training is associated with changes in adipocyte size and lipid metabolism in older women: cross-sectional and longitudinal study by Marek Wilhelm, Terezie Čížková, Klára Daďová, Michal Koc, Jana Neubert, Ondřej Kuda, Jan Gojda, Lenka Rossmeislová, Michaela Šiklová (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13543450.txt.

Description

Marek Wilhelm and colleagues published a 2026 study of how exercise changes fat tissue in older women, looking separately at lifelong activity and a short training block. The cross-sectional part compared 28 long-term physically active women with 29 sedentary peers, all between sixty-one and eighty. Another 23 women completed four months of combined exercise training. Fat samples were examined for cell size, fat-making capacity, gene activity, and lipid and protein profiles.

Both long-active and newly trained women had less fat-cell enlargement, a change the authors link to overall adiposity rather than a reshaped fat-making ability, left unchanged. Long-term activity raised the expression of beta-adrenergic receptors, the switches that let stress hormones trigger fat release, and very-long-chain fatty acid levels in step with fitness. The team frames these as candidate mechanisms connecting exercise to metabolic health in ageing, for confirmation in larger groups.

Catalog record

CREATORMarek Wilhelm, Terezie Čížková, Klára Daďová, Michal Koc, Jana Neubert, Ondřej Kuda, Jan Gojda, Lenka Rossmeislová, Michaela Šiklová
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE48092
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13543450

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