E-cigarette use (vaping) and cigarette smoking are associated with reduced markers of ovarian reserve: a cross-sectional study of 16,087 women
Natalie Getreu, Esther Wainwright, Lauren Crawford, Silvia Nedelcu, Bríd Ní Dhonnabháin, Sofia Rodrigues Vaz, Tharni Vasavan, Helen C. O’Neill · 2026
Read E-cigarette use (vaping) and cigarette smoking are associated with reduced markers of ovarian reserve: a cross-sectional study of 16,087 women by Natalie Getreu, Esther Wainwright, Lauren Crawford, Silvia Nedelcu, Bríd Ní Dhonnabháin, Sofia Rodrigues Vaz, Tharni Vasavan, Helen C. O’Neill (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13543381.txt.
Description
Natalie Getreu and colleagues published a 2026 cross-sectional study linking vaping and smoking to lower markers of ovarian reserve, the remaining egg supply suggested by hormone levels. Data came from 16,087 women aged eighteen to forty-five using a private hormone testing service, excluding reproductive conditions or hormonal contraception. Blood levels of anti-Müllerian hormone and follicle-stimulating hormone were compared across never, former, occasional, and current users of each product.
Current vapers had about 5.6 percent lower anti-Müllerian hormone than never-vapers, with no clear difference in the second hormone. Current smokers fared worse: roughly 9.4 percent lower on the first marker and 7.7 percent higher on the second, a pattern pointing the same way. Occasional and former use showed no associations, and results held after removing dual users. E-cigarettes are marketed as safer than smoking, yet these data tie current use to reduced reserve markers.
Catalog record
| CREATOR | Natalie Getreu, Esther Wainwright, Lauren Crawford, Silvia Nedelcu, Bríd Ní Dhonnabháin, Sofia Rodrigues Vaz, Tharni Vasavan, Helen C. O’Neill |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42162 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |