Pharmacological targeting of kidney fibrosis: druggable mechanisms, translational models, and emerging antifibrotic therapies
Peijian Chen, Siyu Xie, Minglu Ding, Yanhui Chu, Jingru Wang · 2026
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Description
A peer-reviewed research article from Europe PMC (2026). Kidney fibrosis is the final common pathological pathway through which chronic kidney disease progresses to end-stage kidney disease, yet therapies designed specifically to interrupt the core fibrotic process in the kidney are still lacking. This unmet need reflects the biological heterogeneity of kidney fibrosis, the context-dependent interplay among inflammatory, metabolic and mechanical signals, and the limited translational value of many conventional preclinical models.
Catalog record
| CREATOR | Peijian Chen, Siyu Xie, Minglu Ding, Yanhui Chu, Jingru Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 70 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |