Low circulating miR-5193 promotes PD-L1-mediated immune evasion and relates to immune checkpoint inhibitor response in esophageal cancer

Ryo Ishida, Shuhei Komatsu, Hajime Kamiya, Takuma Ohashi, Taisuke Imamura, Jun Kiuchi, Keiji Nishibeppu, Yusuke Takashima, Hiroshi Arakawa, Masateru Yamauchi, Satoshi Hamada, Hiroyuki Kanazawa, Hiroki Shimizu, Tomohiro Arita, Toshiyuki Kosuga, Hirotaka Konishi, Hitoshi Fujiwara, Tomoko Iehara, Hitos · 2026

Read Low circulating miR-5193 promotes PD-L1-mediated immune evasion and relates to immune checkpoint inhibitor response in esophageal cancer by Ryo Ishida, Shuhei Komatsu, Hajime Kamiya, Takuma Ohashi, Taisuke Imamura, Jun Kiuchi, Keiji Nishibeppu, Yusuke Takashima, Hiroshi Arakawa, Masateru Yamauchi, Satoshi Hamada, Hiroyuki Kanazawa, Hiroki Shimizu, Tomohiro Arita, Toshiyuki Kosuga, Hirotaka Konishi, Hitoshi Fujiwara, Tomoko Iehara, Hitos (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13542498.txt.

Description

Low levels of circulating tumor-suppressor microRNAs are associated with cancer progression and poor prognosis. However, their role in immune evasion and response to immune checkpoint inhibitors (ICIs) remains unclear. We aimed to identify a PD-L1-targeting tumor-suppressor microRNA downregulated in esophageal squamous cell carcinoma (ESCC).

Catalog record

CREATORRyo Ishida, Shuhei Komatsu, Hajime Kamiya, Takuma Ohashi, Taisuke Imamura, Jun Kiuchi, Keiji Nishibeppu, Yusuke Takashima, Hiroshi Arakawa, Masateru Yamauchi, Satoshi Hamada, Hiroyuki Kanazawa, Hiroki Shimizu, Tomohiro Arita, Toshiyuki Kosuga, Hirotaka Konishi, Hitoshi Fujiwara, Tomoko Iehara, Hitos
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13542498

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