How past transient viremia shape natural killer cells’ antibody-dependent functions in youth with perinatal HIV
Arianna Rotili, Chiara Pighi, Alessandro Pucci, Alessia Neri, Giuseppe Rubens Pascucci, Nicole Colantoni, Stefania Bernardi, Elena Morrocchi, Federica Betto, Silvia Di Cesare, Donato Amodio, Mathias Lichterfeld, Nicola Cotugno, Paolo Palma · 2026
Read How past transient viremia shape natural killer cells’ antibody-dependent functions in youth with perinatal HIV by Arianna Rotili, Chiara Pighi, Alessandro Pucci, Alessia Neri, Giuseppe Rubens Pascucci, Nicole Colantoni, Stefania Bernardi, Elena Morrocchi, Federica Betto, Silvia Di Cesare, Donato Amodio, Mathias Lichterfeld, Nicola Cotugno, Paolo Palma (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13542491.txt.
Description
Arianna Rotili, Paolo Palma, and a large team studied immune cells in youth with HIV from birth, in work from twenty twenty-six. Even on good drug care, brief spikes of virus can occur. The team asked if such spikes change how natural killer cells kill, when guided by antibodies. Twenty-two youth were split by their past spike history and checked while the virus was held down.
Youth with HIV showed weaker killing than healthy peers overall. Yet those with more past spikes showed stronger killer-cell response when their own plasma was used. With donor plasma, their cells worked just as well. The team reads past spikes as a kind of training for these cells.
Catalog record
| CREATOR | Arianna Rotili, Chiara Pighi, Alessandro Pucci, Alessia Neri, Giuseppe Rubens Pascucci, Nicole Colantoni, Stefania Bernardi, Elena Morrocchi, Federica Betto, Silvia Di Cesare, Donato Amodio, Mathias Lichterfeld, Nicola Cotugno, Paolo Palma |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 62 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |