Effect of rumen-protected standardized dry grape extract supplementation on antioxidant and immune-related gene expression in leukocytes of mid-lactating Fleckvieh cows exposed to natural heat stress
Annalisa Amato, Carmelo Cavallo, Paul Engler, Hoa Bui, Mohammed el Amine Benarbia, Andrea Minuti, Erminio Trevisi, Anna Antonella Spina, Concetta Molè, Maria Giovanna Ciliberti, Marzia Albenzio, Luigi Liotta, Vincenzo Lopreiato · 2026
Read Effect of rumen-protected standardized dry grape extract supplementation on antioxidant and immune-related gene expression in leukocytes of mid-lactating Fleckvieh cows exposed to natural heat stress by Annalisa Amato, Carmelo Cavallo, Paul Engler, Hoa Bui, Mohammed el Amine Benarbia, Andrea Minuti, Erminio Trevisi, Anna Antonella Spina, Concetta Molè, Maria Giovanna Ciliberti, Marzia Albenzio, Luigi Liotta, Vincenzo Lopreiato (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13542447.txt.
Description
Annalisa Amato and colleagues tested gut-guarded grape extract as a heat shield for dairy cow blood cells. Published in 2026, the study fed 30 Fleckvieh cows either plain feed or feed with 470 mg of grape extract per cow daily for 35 days. Heat stress upsets cow redox balance and immune fire, cutting output and breeding success.
Blood draws on days 0, 17, and 35 showed the extract lifting two rust-fighting genes, GPX1 and GSR, most clearly at day 17. During a heat wave at day 35, fed cows showed higher IL1B and IL10 gene activity, hinting at steadier immune control. The authors read the pattern as grape extract backing white-cell tuning to heat stress. Readers get a feed-based lever for cow toughness in hotter summers.
Catalog record
| CREATOR | Annalisa Amato, Carmelo Cavallo, Paul Engler, Hoa Bui, Mohammed el Amine Benarbia, Andrea Minuti, Erminio Trevisi, Anna Antonella Spina, Concetta Molè, Maria Giovanna Ciliberti, Marzia Albenzio, Luigi Liotta, Vincenzo Lopreiato |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |