Hypoadiponectinemia does not enhance anxiety-like behaviour in a lean PCOS-like mouse model
Manisha Samad, Joakim Ek, Josefin Kataoka, Eva Lindgren, Claes Ohlsson, Ingrid Wernstedt Asterholm, Elisabet Stener-Victorin, Anna Benrick · 2026
Read Hypoadiponectinemia does not enhance anxiety-like behaviour in a lean PCOS-like mouse model by Manisha Samad, Joakim Ek, Josefin Kataoka, Eva Lindgren, Claes Ohlsson, Ingrid Wernstedt Asterholm, Elisabet Stener-Victorin, Anna Benrick (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13542225.txt.
Description
Manisha Samad and co-authors test if low adiponectin drives worry in a PCOS-like state, in work dated 2026. PCOS is a hormone state in women tied to more worry and low mood. Adiponectin, a fat-made hormone helper, runs low in PCOS and has been tied to poor mental health. The team read its levels in women with and without PCOS, split by weight.
Levels ran lower in PCOS and tracked mental scores in leaner women. In mice bred for a PCOS-like state, worry acts rose. Cutting adiponectin by two thirds did not worsen those acts, though. Low levels alone, with no hormone excess, did not drive worry.
Catalog record
| CREATOR | Manisha Samad, Joakim Ek, Josefin Kataoka, Eva Lindgren, Claes Ohlsson, Ingrid Wernstedt Asterholm, Elisabet Stener-Victorin, Anna Benrick |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |