Age-related loss of Y chromosome is associated with mortality after ST-segment elevation myocardial infarction
Nan Li, Jiannan Li, Yu Tan, Runzhen Chen, Xiaoxiao Zhao, Peng Zhou, Chen Liu, Jinying Zhou, Yi Chen, Shaodi Yan, Hanjun Zhao, Li Song, Hongbing Yan · 2026
Read Age-related loss of Y chromosome is associated with mortality after ST-segment elevation myocardial infarction by Nan Li, Jiannan Li, Yu Tan, Runzhen Chen, Xiaoxiao Zhao, Peng Zhou, Chen Liu, Jinying Zhou, Yi Chen, Shaodi Yan, Hanjun Zhao, Li Song, Hongbing Yan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13542210.txt.
Description
Nan Li and colleagues tied age-related Y chromosome loss to death risk after major heart attacks. Published in 2026, the study tracked 928 men treated with urgent artery-opening procedures for ST-elevation heart attacks. Y loss in blood cells, common with aging, was already linked to heart disease, but its role right after such attacks was murky.
Over a median near-four-year follow-up, 93 men died. Men with Y loss in at least 18 percent of blood cells faced roughly double to two-and-a-half times the death risk at one, two, and three years versus men below that line. Age and other factors were allowed for. The link held for men without a prior attack but not for those with one. The authors present high Y loss as a new risk-sorting marker after such attacks.
Catalog record
| CREATOR | Nan Li, Jiannan Li, Yu Tan, Runzhen Chen, Xiaoxiao Zhao, Peng Zhou, Chen Liu, Jinying Zhou, Yi Chen, Shaodi Yan, Hanjun Zhao, Li Song, Hongbing Yan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |