Correlation of [18F]SiTATE-PET-tracer with somatostatin receptor expression in meningiomas: an exploratory ex vivo histological pilot study
Rieke Gerdes, Jens Schittenhelm, Stephan Singer, Gerald Reischl, Hannes Becker, Marcos Tatagiba, Salvador G. Castaneda-Vega, Christian la Fougère, Benjamin Bender, Nils F. Trautwein · 2026
Read Correlation of [18F]SiTATE-PET-tracer with somatostatin receptor expression in meningiomas: an exploratory ex vivo histological pilot study by Rieke Gerdes, Jens Schittenhelm, Stephan Singer, Gerald Reischl, Hannes Becker, Marcos Tatagiba, Salvador G. Castaneda-Vega, Christian la Fougère, Benjamin Bender, Nils F. Trautwein (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13542035.txt.
Description
Rieke Gerdes and co-authors run a small pilot study in 2026 on brain tumor scans. Meningiomas are tumors that often carry a receptor that a tracer drug can target in PET scans. The tracer used here has perks over older ones, such as longer life and sharper images, but it lacks formal approval. The team compared scan uptake in tumor tissue with lab stains for the receptor in samples from twelve patients.
Scan uptake tracked the lab stain closely, and high stain tumors took up much more tracer than low stain ones. Two ways of drawing tumor volume from the scan both missed the true size in some cases when set against MRI. Readers learn both the promise and the sizing limits of this scan method.
Catalog record
| CREATOR | Rieke Gerdes, Jens Schittenhelm, Stephan Singer, Gerald Reischl, Hannes Becker, Marcos Tatagiba, Salvador G. Castaneda-Vega, Christian la Fougère, Benjamin Bender, Nils F. Trautwein |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |