Rethinking surgical strategy for margin-positive only T1 colorectal cancer: a multicenter retrospective cohort study
Jin Hyeong Park, Chang Hwan Kim, Dae Hee Pyo, Jong Kyung Park, Chaedong Lim, Ji Hoon Kim, Bong-Hyeon Kye, Hyung Jin Kim · 2026
Read Rethinking surgical strategy for margin-positive only T1 colorectal cancer: a multicenter retrospective cohort study by Jin Hyeong Park, Chang Hwan Kim, Dae Hee Pyo, Jong Kyung Park, Chaedong Lim, Ji Hoon Kim, Bong-Hyeon Kye, Hyung Jin Kim (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13541859.txt.
Description
Jin Hyeong Park and colleagues ask a surgical question in 2026. Can major bowel surgery be skipped in one narrow case? The case is early colorectal cancer removed by endoscopy. The only warning sign is a positive cut edge. Guidelines push toward radical resection when any risk factor appears. That operation carries real costs.
Three Korean referral centres reviewed 250 patients. All had radical surgery after endoscopic removal. One in ten had cancer in nearby lymph nodes. Spread into vessels predicted nodal disease. A KRAS mutation predicted it too. Twenty-two patients had margin positivity as their only risk factor. None of those twenty-two had nodal spread.
Catalog record
| CREATOR | Jin Hyeong Park, Chang Hwan Kim, Dae Hee Pyo, Jong Kyung Park, Chaedong Lim, Ji Hoon Kim, Bong-Hyeon Kye, Hyung Jin Kim |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35625 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |