The Preliminary Efficacy and Feasibility of SMILE Serious Game for Adolescents and Young Adults: Protocol for Cluster Randomized Multisite Adaptive Trial Design
Ewelina Smoktunowicz, Jan Maciejewski, Magdalena Lesnierowska, Magdalena Pietrzak, Franziska Großwendt, Gwendolyn Mayer, Jobst-Hendrik Schultz, Nelli Tschobur, Mel McKendrick, Helen Stocks, Francesca Floris, Dina Guglielmi, Zouhair Haddi, Carlo Mazzola, Izidor Mlakar, Urška Smrke, Laura Fernández Ga · 2026
Read The Preliminary Efficacy and Feasibility of SMILE Serious Game for Adolescents and Young Adults: Protocol for Cluster Randomized Multisite Adaptive Trial Design by Ewelina Smoktunowicz, Jan Maciejewski, Magdalena Lesnierowska, Magdalena Pietrzak, Franziska Großwendt, Gwendolyn Mayer, Jobst-Hendrik Schultz, Nelli Tschobur, Mel McKendrick, Helen Stocks, Francesca Floris, Dina Guglielmi, Zouhair Haddi, Carlo Mazzola, Izidor Mlakar, Urška Smrke, Laura Fernández Ga (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13541232.txt.
Description
Ewelina Smoktunowicz and co-authors set out a trial plan for a mental health game in a 2026 protocol paper. Many teens and young adults never get timely help for mental health trouble. The game, called SMILE, teaches coping skills from cognitive behavioral therapy in play form. The trial spans many sites across Europe and adapts its design as results come in.
Whole clusters of participants are assigned by chance to the game or comparison care. The team will track whether young people accept the game, whether sites can run it, and whether symptoms ease early. Reach counts as much as effect size at this stage. A careful plan like this keeps a soft tool honest before wider rollout.
Catalog record
| CREATOR | Ewelina Smoktunowicz, Jan Maciejewski, Magdalena Lesnierowska, Magdalena Pietrzak, Franziska Großwendt, Gwendolyn Mayer, Jobst-Hendrik Schultz, Nelli Tschobur, Mel McKendrick, Helen Stocks, Francesca Floris, Dina Guglielmi, Zouhair Haddi, Carlo Mazzola, Izidor Mlakar, Urška Smrke, Laura Fernández Ga |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 62 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |