The impact of symptoms and illness insight on treatment adherence in first-episode psychosis: a one-year follow-up study using therapeutic drug monitoring

Juhani Leijala, Olli Kampman, Teemu Gunnar, Jaana Suvisaari · 2026

Read The impact of symptoms and illness insight on treatment adherence in first-episode psychosis: a one-year follow-up study using therapeutic drug monitoring by Juhani Leijala, Olli Kampman, Teemu Gunnar, Jaana Suvisaari (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13540956.txt.

Description

Juhani Leijala and colleagues follow new psychosis patients in a 2026 study. They asked what predicts steady use of antipsychotic medicine. Blood levels judged adherence here. Self-report and clinician guesses are notoriously unreliable. The patients were in a first episode of psychosis.

Seventy-eight patients were assessed three times over one year. The visits fell at entry, two months, and twelve months. Scales covered symptoms, insight, and functioning. Adherence slipped over the year as a whole. Stronger current positive symptoms lowered the odds of adherence. Past non-adherence also predicted later behaviour. Insight and negative symptoms showed no steady link. Functioning showed none either.

Catalog record

CREATORJuhani Leijala, Olli Kampman, Teemu Gunnar, Jaana Suvisaari
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45612
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13540956

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