Emergence of two novel HIV-1 Circulating Recombinant Forms (CRF190_0708 and CRF191_0708): molecular characterization and clinical insights from a five-year study in Yunnan, China
Li Gao, Wei Chang, Yuanlu Shu, Yang Liu, Mi Zhang, Qian Yang, Jianjian Li, HongYe Pai, Lingling Huang, Yongjiao Chen, Zhiqing Yang, Fei Lu, Xingqi Dong, Yue Feng, Xueshan Xia · 2026
Read Emergence of two novel HIV-1 Circulating Recombinant Forms (CRF190_0708 and CRF191_0708): molecular characterization and clinical insights from a five-year study in Yunnan, China by Li Gao, Wei Chang, Yuanlu Shu, Yang Liu, Mi Zhang, Qian Yang, Jianjian Li, HongYe Pai, Lingling Huang, Yongjiao Chen, Zhiqing Yang, Fei Lu, Xingqi Dong, Yue Feng, Xueshan Xia (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13540875.txt.
Description
Li Gao leads a 2026 study of HIV strains in Yunnan, China. The team found two newly recognised recombinant forms of HIV-1. Recombinants arise when two virus strains mix inside one person. Tracking them shows how the epidemic keeps changing. The patients were heterosexual and not yet on treatment.
Genes from 636 patients were analysed for diversity and resistance. Drug resistance appeared in about six percent of cases. One signature mutation led the list. Full genomes revealed two second-generation recombinants. Their names are CRF190_0708 and CRF191_0708. Their ancestors date to about 1999 and about 2010. Over five years, viral rebound was more common in the first group.
Catalog record
| CREATOR | Li Gao, Wei Chang, Yuanlu Shu, Yang Liu, Mi Zhang, Qian Yang, Jianjian Li, HongYe Pai, Lingling Huang, Yongjiao Chen, Zhiqing Yang, Fei Lu, Xingqi Dong, Yue Feng, Xueshan Xia |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45739 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |