Global disparities in COVID-19 vaccine coverage associated with trajectories of SARS-CoV-2 adaptation
Lingyue Yang, Ziqin Zhou, Qiushi Lin, Yuyang Chen, Yamin Sun, Zengmiao Wang · 2026
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Description
Lingyue Yang and five colleagues analyse, in a 2026 study, whether uneven COVID-19 vaccine coverage across countries shaped how the coronavirus evolved. More than thirteen million viral genomes from 86 countries, collected between March 2020 and September 2022, underpin the analysis.
Before the Omicron variant took over, medium levels of adjusted vaccine coverage were linked with faster protein-changing evolution in part of the spike protein, while high coverage showed no significant link. Once Omicron dominated, the association vanished, possibly because that variant escapes immunity so well. Death rates and viral adaptation also moved together. The authors argue for fast, fair vaccine sharing in future pandemics.
Catalog record
| CREATOR | Lingyue Yang, Ziqin Zhou, Qiushi Lin, Yuyang Chen, Yamin Sun, Zengmiao Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50719 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |