Accuracy of Retinal Pigment Epithelium (RPE) undulations (Oscillatory sign) as an optical coherence tomography biomarker of acute RPE tears
Manoj P. Shettigar, Jay Chhablani, Mudit Tyagi, Ritesh Narula, Raja Narayanan · 2026
Read Accuracy of Retinal Pigment Epithelium (RPE) undulations (Oscillatory sign) as an optical coherence tomography biomarker of acute RPE tears by Manoj P. Shettigar, Jay Chhablani, Mudit Tyagi, Ritesh Narula, Raja Narayanan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13540068.txt.
Description
Manoj P Shettigar and four colleagues test, in a 2026 imaging study, whether wavy undulations in the pigment layer at the back of the eye warn of a tear in that layer. Tears are a damaging complication of wet age-related macular degeneration, a common cause of sight loss in older adults.
Records covered 936 eyes with the disease, of which 79 had documented tears confirmed by photographs and autofluorescence imaging. The wavy sign, nicknamed the oscillatory sign, appeared in just under half the torn eyes, giving modest sensitivity. Its strength lay elsewhere: it was almost never seen in eyes without tears, and its absence predicted an intact layer with high reliability.
Catalog record
| CREATOR | Manoj P. Shettigar, Jay Chhablani, Mudit Tyagi, Ritesh Narula, Raja Narayanan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 18923 |
| LICENSE | https://creativecommons.org/publicdomain/zero/1.0 |
| RIGHTS | CC0 |
| SOURCE | Europe PMC |