Hepatorenal protective and antitumor effects of astaxanthin-loaded chitosan nanoparticles against ehrlich ascites carcinoma in mice through antioxidant, anti-inflammatory, and apoptotic pathway modulation
Mohammed Saleh Alfawaz, Ekramy M Elmorsy, Huda A Al Doghaither, Ayat B Al-Ghafari, Ahd A Mansour, Ahmad Najem Alshammari, Manal S Fawzy, Mona M Elghareeb · 2026
Read Hepatorenal protective and antitumor effects of astaxanthin-loaded chitosan nanoparticles against ehrlich ascites carcinoma in mice through antioxidant, anti-inflammatory, and apoptotic pathway modulation by Mohammed Saleh Alfawaz, Ekramy M Elmorsy, Huda A Al Doghaither, Ayat B Al-Ghafari, Ahd A Mansour, Ahmad Najem Alshammari, Manal S Fawzy, Mona M Elghareeb (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13539798.txt.
Description
Mohammed Saleh Alfawaz and seven colleagues report a 2026 mouse study of astaxanthin, a red pigment from algae with strong antioxidant action, packed into tiny chitosan particles. They tested it against Ehrlich ascites carcinoma, a fast-growing tumor model that also damages the liver and kidneys.
Ninety female mice were split into six groups, some healthy and some carrying the tumor, with plain astaxanthin compared against the particle form. The particle version slowed tumor growth more, lifted survival, restored antioxidant defenses, and lowered inflammatory signals. Tissue slides showed less injury to liver and kidney. The team reads the results as evidence that the packaging improves a poorly absorbed compound.
Catalog record
| CREATOR | Mohammed Saleh Alfawaz, Ekramy M Elmorsy, Huda A Al Doghaither, Ayat B Al-Ghafari, Ahd A Mansour, Ahmad Najem Alshammari, Manal S Fawzy, Mona M Elghareeb |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 73812 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |