Skin symptoms and their impact on quality-of-life in adults with osteogenesis imperfecta
Winnie Liu, Jonathan Xu, Apoorva Salvi, Suephy Chen, Lars Folkestad, Jorg Oliver Semler, Eric Orwoll · 2026
Read Skin symptoms and their impact on quality-of-life in adults with osteogenesis imperfecta by Winnie Liu, Jonathan Xu, Apoorva Salvi, Suephy Chen, Lars Folkestad, Jorg Oliver Semler, Eric Orwoll (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13538963.txt.
Description
Liu and six co-authors surveyed skin complaints in brittle bone disease in this study from twenty twenty-six. Osteogenesis imperfecta stems from faulty collagen, a protein also plentiful in skin. Yet its skin effects were barely documented. Over eight hundred adults, most with the condition, answered a twenty-item symptom survey.
Adults with the disease reported far more skin symptoms than controls. Easy bruising topped the list, followed by dry skin and heavy sweating. Women reported more symptoms than men. Over half found their skin bothersome, with quality-of-life scores to match. Severe disease leaned toward itch and rashes, mild disease toward bruising and fragile nails. The authors urge doctors to treat skin as part of the condition.
Catalog record
| CREATOR | Winnie Liu, Jonathan Xu, Apoorva Salvi, Suephy Chen, Lars Folkestad, Jorg Oliver Semler, Eric Orwoll |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |