Risk of Severe Hypoglycemia Associated With Concomitant Use of Sulfonylureas and Amiodarone

Sungho Bea, Hyesung Lee, Young Min Cho, You‐Jung Choi, Ju‐Young Shin, Katsiaryna Bykov · 2026

Read Risk of Severe Hypoglycemia Associated With Concomitant Use of Sulfonylureas and Amiodarone by Sungho Bea, Hyesung Lee, Young Min Cho, You‐Jung Choi, Ju‐Young Shin, Katsiaryna Bykov (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13538823.txt.

Description

Sungho Bea and colleagues weigh severe low blood sugar risk when a heart rhythm drug joins a common diabetes pill in a 2026 Korean claims study. The rhythm drug slows liver breakdown of the diabetes pill, plausibly raising its levels. Among 12,730 adults with type 2 diabetes starting rhythm therapy while on the pill class, starters of the drug in question were weighted against starters of three rival rhythm drugs.

After weighting, starting the drug in question carried nearly double the hazard of severe low blood sugar needing hospital or emergency care versus the rivals. The elevation persisted across sensitivity and subgroup checks. The authors urge caution and close monitoring when the two medicines combine, given how widely the pill class remains used.

Catalog record

CREATORSungho Bea, Hyesung Lee, Young Min Cho, You‐Jung Choi, Ju‐Young Shin, Katsiaryna Bykov
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13538823

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