Neurons run on fat
Rui Qi Teo, Gio Fidelito, Matthew J. Watt, Garron T. Dodd · 2026
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Description
Rui Qi Teo, Gio Fidelito, Matthew J Watt, and Garron T Dodd wrote a 2026 review on a surprise fuel for brain cells. Neurons were long thought to run almost wholly on sugar. Three labs have now shown that neurons can also burn long-chain fats for energy.
A fat-moving enzyme called DDHD2 sits at the heart of the new story. It frees fats inside the neuron so they can be burned when sugar runs short. Support cells already pass fuels to neurons, and fat now joins that menu. The shift in view could matter for diseases where brain energy fails.
Catalog record
| CREATOR | Rui Qi Teo, Gio Fidelito, Matthew J. Watt, Garron T. Dodd |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |