Pilot study on RECAF (Receptor for Alpha-Fetoprotein) expression in pediatric acute leukemia: insights from flow cytometry analysis
Soha Raouf Youssef, Mohamed Hany Mohammady, Shams ElDoha Galal ElDin Zaiema · 2026
Read Pilot study on RECAF (Receptor for Alpha-Fetoprotein) expression in pediatric acute leukemia: insights from flow cytometry analysis by Soha Raouf Youssef, Mohamed Hany Mohammady, Shams ElDoha Galal ElDin Zaiema (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13538328.txt.
Description
Soha Youssef, Mohamed Mohammady, and Shams Zaiema pilot a cell marker, RECAF, that may flag childhood acute leukemia and track its remnants. RECAF is a receptor for a fetal protein that is abnormally re-expressed in many tumors. Their 2026 pilot study ran flow cytometry on 80 child patients. Forty had the lymphoid form of acute leukemia and 40 the myeloid form, alongside 40 healthy peers matched for age and sex.
Marker levels ran significantly higher in the leukemia patients than in healthy controls. A cut-off of 13.31 percent positive expression separated marker-high leukemia from marker-low cases and healthy sets. The team reads the marker as a way to distinguish leukemic blast cells at first diagnosis. They pitch it next as a tool for monitoring the last measurable remnants of the disease after treatment, a use still to be proved.
Catalog record
| CREATOR | Soha Raouf Youssef, Mohamed Hany Mohammady, Shams ElDoha Galal ElDin Zaiema |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 78 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |