No serological association between Porphyromonas gingivalis or Prevotella intermedia and early spondyloarthritis: analysis from the DESIR cohort
Franck Zekre, Tiphany Neel, Mireille Paul, Myriam Normand, Anne Tournadre, Hubert Marotte · 2026
Read No serological association between Porphyromonas gingivalis or Prevotella intermedia and early spondyloarthritis: analysis from the DESIR cohort by Franck Zekre, Tiphany Neel, Mireille Paul, Myriam Normand, Anne Tournadre, Hubert Marotte (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13538221.txt.
Description
Franck Zekre and co-authors test blood antibodies to two gum bacteria in early spine arthritis in a 2026 cohort analysis. Both bacteria drive gum disease and have been linked to joint arthritis, raising questions about spine disease. Serum from 554 people in a French early back pain cohort was tested and sorted into spine arthritis types, with or without skin or bowel features, plus chronic back pain controls. Smoking was also considered.
Antibody levels overlapped strongly across all groups, with no clear gap between any arthritis type and controls for either bacterium. Adjusting for age, sex, weight, and smoking changed nothing, and smoking itself showed no sway on patterns. The authors conclude that blood responses to these two bacteria show no major link to early spine arthritis, while wider mouth imbalance remains possible.
Catalog record
| CREATOR | Franck Zekre, Tiphany Neel, Mireille Paul, Myriam Normand, Anne Tournadre, Hubert Marotte |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26924 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |