mTORC1 Promotes SARS-CoV-2 Replication and Attenuates Type I Interferon Responses in the Alveolar Epithelium: A Computational and Experimental Study
Achyudhan R. Kutuva, Henrique AL Ribeiro, Felipe T. Lima, Matthew A. Schaller, Borna Mehrad, Reinhard Laubenbacher · 2026
Read mTORC1 Promotes SARS-CoV-2 Replication and Attenuates Type I Interferon Responses in the Alveolar Epithelium: A Computational and Experimental Study by Achyudhan R. Kutuva, Henrique AL Ribeiro, Felipe T. Lima, Matthew A. Schaller, Borna Mehrad, Reinhard Laubenbacher (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13538202.txt.
Description
Achyudhan Kutuva and co-authors study a growth switch that helps the COVID virus copy itself in lung lining cells in a 2026 paper. The switch had been tied to coronavirus harm, but its exact hand in blunting early virus alarms was unsettled.
Human lung tissue tests show that blocking the switch with a drug cuts virus growth and lifts the alarm signal. A logic model of the cell's signal web, checked against dozens of past reads, backs that dual role. Thousands of tweaked model webs test how sturdy the claim is. The study marks the switch as a drug lead for lung infection.
Catalog record
| CREATOR | Achyudhan R. Kutuva, Henrique AL Ribeiro, Felipe T. Lima, Matthew A. Schaller, Borna Mehrad, Reinhard Laubenbacher |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 78 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |