Chemical profiling, biological evaluation, and QSAR-informed metabolite prioritization of Hypericum ekerii: a first report on antioxidant, enzyme inhibitory, and cytotoxic activities
Gokhan Zengin, Sakina Yagi, Mehmet Veysi Cetiz, Abdullahi Ibrahim Uba, Filip Nikolić, Uroš Gašić, Mehmet Maruf Balos, Ahmet Erharman, Nurettin Dogan, Ismail Koyuncu, Ismail Yapıcı, Ilhami Gulcin · 2026
Read Chemical profiling, biological evaluation, and QSAR-informed metabolite prioritization of Hypericum ekerii: a first report on antioxidant, enzyme inhibitory, and cytotoxic activities by Gokhan Zengin, Sakina Yagi, Mehmet Veysi Cetiz, Abdullahi Ibrahim Uba, Filip Nikolić, Uroš Gašić, Mehmet Maruf Balos, Ahmet Erharman, Nurettin Dogan, Ismail Koyuncu, Ismail Yapıcı, Ilhami Gulcin (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13537189.txt.
Description
Gokhan Zengin and co-authors give a first full profile of a little studied plant in the St John wort family. Their paper from 2026 covers Hypericum ekerii, named in 2017 and near unmapped for its chemistry and effects. Extracts were made from its above ground parts with four solvents.
One mix, acetone and water, held the most plant phenols and gave the strongest radical clearing and reducing power. Chemical scans named ninety nine compounds in the extracts, from plant acids to pigments. Enzyme tests showed unlike strengths by solvent: some extracts led on brain or skin enzymes, and the water extract led on a sugar enzyme. Cell harm was limited overall, with weak selectivity.
Catalog record
| CREATOR | Gokhan Zengin, Sakina Yagi, Mehmet Veysi Cetiz, Abdullahi Ibrahim Uba, Filip Nikolić, Uroš Gašić, Mehmet Maruf Balos, Ahmet Erharman, Nurettin Dogan, Ismail Koyuncu, Ismail Yapıcı, Ilhami Gulcin |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 65 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |