Intratumor habitat aware deep learning framework for preoperative lymph node metastasis prediction in laryngeal carcinoma

Wencan Wang, Lingyu Zhang, Junhong Zhang, Xinyu Li, Wenfeng Wei, Li Liang, Shiwen Li, Haomiao Ma, Xuhui Zhao, Qian Zhang, Huina Guo, Yanhong Hao, Hua Zhang, Feng Gao, Jianxin Zhang, Lingjie Wang · 2026

Read Intratumor habitat aware deep learning framework for preoperative lymph node metastasis prediction in laryngeal carcinoma by Wencan Wang, Lingyu Zhang, Junhong Zhang, Xinyu Li, Wenfeng Wei, Li Liang, Shiwen Li, Haomiao Ma, Xuhui Zhao, Qian Zhang, Huina Guo, Yanhong Hao, Hua Zhang, Feng Gao, Jianxin Zhang, Lingjie Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13536815.txt.

Description

Wencan Wang leads a 2026 multicenter study building a deep learning tool to predict neck lymph node spread in voice box cancer before surgery. Standard scans miss many small spread sites, so the tool reads contrast scans while mapping varied zones inside the main tumor. Records for 381 patients supplied training and outside testing. Performance was compared with standard image features and with a three-dimensional learning model, alone and combined.

The zone-aware model beat both comparison models in outside testing. A combined stack of all three models scored highest overall. Both the zone-aware and combined models also separated patients into survival groups with clearly different outcomes. The authors present the tool as support for personal surgical planning, pending wider validation.

Catalog record

CREATORWencan Wang, Lingyu Zhang, Junhong Zhang, Xinyu Li, Wenfeng Wei, Li Liang, Shiwen Li, Haomiao Ma, Xuhui Zhao, Qian Zhang, Huina Guo, Yanhong Hao, Hua Zhang, Feng Gao, Jianxin Zhang, Lingjie Wang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13536815

Browse the full library · About the Tower of Babel