Acute acalculous cholecystitis and blackwater fever with acute kidney injury in children with malaria: case series and literature review

Marco Cugliari, Francesca Piacentini, Sara M. M. A. Montorfani, Obalim Fiddy, Sara Testa · 2026

Read Acute acalculous cholecystitis and blackwater fever with acute kidney injury in children with malaria: case series and literature review by Marco Cugliari, Francesca Piacentini, Sara M. M. A. Montorfani, Obalim Fiddy, Sara Testa (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13536800.txt.

Description

Marco Cugliari and colleagues describe four Ugandan children with malaria who developed gallbladder inflammation without stones in a 2026 case series with a literature review. All four children also showed blackwater fever, marked by dark urine from blood breakdown, plus severe kidney injury. Two children needed dialysis. Care for the gallbladder stayed conservative without surgery, and outcomes were tracked alongside past reports.

All four children recovered both gallbladder and kidney function. The review found 28 earlier cases of malaria-linked gallbladder inflammation, only seven in children, mostly treated outside high-burden regions. Most past patients also recovered with conservative care. The authors argue the condition is likely missed where malaria is common, and they offer practical steps for early checks and care.

Catalog record

CREATORMarco Cugliari, Francesca Piacentini, Sara M. M. A. Montorfani, Obalim Fiddy, Sara Testa
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35952
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13536800

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