A novel strategy for soft tissue sarcoma lattice radiotherapy: integrating X-ray andγ-ray technologies to optimize dose delivery
Zhongfei Wang, Qinghui Yun, Te Zhang, Xiaohuan Sun, Wei Wang, Jie Duan, Liting Chen, Yue Gao, Ziqi An, Changhao Liu, Jian Zang, Pengfei Zhang, Lina Zhao · 2026
Read A novel strategy for soft tissue sarcoma lattice radiotherapy: integrating X-ray andγ-ray technologies to optimize dose delivery by Zhongfei Wang, Qinghui Yun, Te Zhang, Xiaohuan Sun, Wei Wang, Jie Duan, Liting Chen, Yue Gao, Ziqi An, Changhao Liu, Jian Zang, Pengfei Zhang, Lina Zhao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13536791.txt.
Description
Zhongfei Wang and colleagues compare radiation plans for soft tissue sarcoma in a 2026 dose study using a hybrid platform that combines a standard accelerator with focused gamma rays. Lattice therapy places small high-dose spots inside large tumors while standard doses cover the wider target. Plans for ten cases were built for the hybrid system and for a standard machine, then compared on spot coverage, dose falloff, and healthy tissue exposure.
Hybrid plans delivered higher doses to the high-dose spots and showed steeper falloff beyond them, with lower doses at tumor margins. Exposure to nearby nerves and bones also fell or held steady despite the stronger spot doses. The authors present the hybrid approach as a promising way to sharpen lattice therapy while sparing normal tissue.
Catalog record
| CREATOR | Zhongfei Wang, Qinghui Yun, Te Zhang, Xiaohuan Sun, Wei Wang, Jie Duan, Liting Chen, Yue Gao, Ziqi An, Changhao Liu, Jian Zang, Pengfei Zhang, Lina Zhao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26483 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |