Is active surveillance of CIN2 always appropriate? Clinical outcomes and factors associated with progression and regression over 48 months in an HPV-positive cohort
Maria Teresa Bruno, Alessia Pagana, Tiziana Aiello, Elena Pivetti, Antonino Giovanni Cavallaro, Mattia Tarascio, Marco Marzio Panella, Gaetano Valenti · 2026
Read Is active surveillance of CIN2 always appropriate? Clinical outcomes and factors associated with progression and regression over 48 months in an HPV-positive cohort by Maria Teresa Bruno, Alessia Pagana, Tiziana Aiello, Elena Pivetti, Antonino Giovanni Cavallaro, Mattia Tarascio, Marco Marzio Panella, Gaetano Valenti (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13536585.txt.
Description
Maria Teresa Bruno and colleagues ask in 2026 whether active surveillance is always right for CIN2, a mid-grade cervical cell change, in HPV-positive women. Watching instead of cutting can avoid overtreatment, mainly in young women. Records followed women whose lesions were confirmed and then monitored for up to 48 months.
About six in ten lesions cleared on their own, while a quarter progressed and the rest stayed put. High-grade cell test results and HPV types 16 or 18 marked higher progression risk. Careful risk sorting is needed rather than one rule for all.
Catalog record
| CREATOR | Maria Teresa Bruno, Alessia Pagana, Tiziana Aiello, Elena Pivetti, Antonino Giovanni Cavallaro, Mattia Tarascio, Marco Marzio Panella, Gaetano Valenti |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34280 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |