Speech-based relapse prediction in psychosis using explainable AI: Protocol for the international multicentre observational TRUSTING study
Roya Melanie Hüppi, Lucía Bautista, Giacomo Cecere, Wolfgang Omlor, Sandra Anna Just, Sanne Koops, Musarrat Hussain, Enrico Tedeschi, Stephan Benke-Bruderer, Emre Bora, John Lyne, Stefan Kaiser, Elodie Sprüngli-Toffel, Matthias Kirschner, Karl Øyvind Mikalsen, Lars Ailo Bongo, Erik Van der Eycken, F · 2026
Read Speech-based relapse prediction in psychosis using explainable AI: Protocol for the international multicentre observational TRUSTING study by Roya Melanie Hüppi, Lucía Bautista, Giacomo Cecere, Wolfgang Omlor, Sandra Anna Just, Sanne Koops, Musarrat Hussain, Enrico Tedeschi, Stephan Benke-Bruderer, Emre Bora, John Lyne, Stefan Kaiser, Elodie Sprüngli-Toffel, Matthias Kirschner, Karl Øyvind Mikalsen, Lars Ailo Bongo, Erik Van der Eycken, F (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13536150.txt.
Description
Roya Melanie Hueppi and co-authors lay out the plan for TRUSTING, a global study that uses speech to warn of relapse in psychosis. Relapses shape the course of these disorders, yet early signs differ per person and slip past routine visits. Speech offers a measurable signal that phones can gather often.
The study will follow two hundred forty adults with psychotic disorders who are stable or at risk, plus a matched healthy group. Six sites will work in six languages over six months. A phone app will collect weekly speech tasks, tapping data, and short reports on mood, sleep, anxiety, drug use, and pill taking. The goal is a fair, explainable tool that flags rising risk in time to help. Feasibility and ease of use will be judged alongside accuracy.
Catalog record
| CREATOR | Roya Melanie Hüppi, Lucía Bautista, Giacomo Cecere, Wolfgang Omlor, Sandra Anna Just, Sanne Koops, Musarrat Hussain, Enrico Tedeschi, Stephan Benke-Bruderer, Emre Bora, John Lyne, Stefan Kaiser, Elodie Sprüngli-Toffel, Matthias Kirschner, Karl Øyvind Mikalsen, Lars Ailo Bongo, Erik Van der Eycken, F |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 57 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |