Delivery strategies for malaria chemoprevention in the post-discharge management of children hospitalised with severe anaemia or severe malaria: protocol for a cluster randomised controlled implementation trial in Benin

Manfred Accrombessi, Landry Assongba, Carole Khairallah, Tao Chen, Benjamine Tchéhoundjè, Edouard Dangbénon, Daleb Abdoulaye, Jeanne Perpétue Vincent, Juliet Otieno Awori, Adrian J F Luty, Jenna Hoyt, Amanda McCoy, Eve Worrall, Valérie Briand, Feiko O ter Kuile, Achille Massougbodji, Jenny Hill · 2026

Read Delivery strategies for malaria chemoprevention in the post-discharge management of children hospitalised with severe anaemia or severe malaria: protocol for a cluster randomised controlled implementation trial in Benin by Manfred Accrombessi, Landry Assongba, Carole Khairallah, Tao Chen, Benjamine Tchéhoundjè, Edouard Dangbénon, Daleb Abdoulaye, Jeanne Perpétue Vincent, Juliet Otieno Awori, Adrian J F Luty, Jenna Hoyt, Amanda McCoy, Eve Worrall, Valérie Briand, Feiko O ter Kuile, Achille Massougbodji, Jenny Hill (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13536061.txt.

Description

Manfred Accrombessi and co-authors published a trial protocol in 2026 for testing ways to deliver malaria prevention medicine to children leaving hospital in Benin. Children discharged after severe anemia or severe malaria often fall ill again or die in the weeks after. A preventive drug course after discharge cuts those risks and is now advised worldwide, but the best delivery route is unsettled.

Whole villages near two hospitals will be assigned by lot to different delivery and reminder schemes. The trial tracks course completion first, then readmissions, clinic visits, and deaths. It also probes how families and clinics judge each scheme. Results should guide programs across West Africa.

Catalog record

CREATORManfred Accrombessi, Landry Assongba, Carole Khairallah, Tao Chen, Benjamine Tchéhoundjè, Edouard Dangbénon, Daleb Abdoulaye, Jeanne Perpétue Vincent, Juliet Otieno Awori, Adrian J F Luty, Jenna Hoyt, Amanda McCoy, Eve Worrall, Valérie Briand, Feiko O ter Kuile, Achille Massougbodji, Jenny Hill
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE50 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13536061

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