Longitudinal Serum Uric Acid Variation and Risk of Major Adverse Cardiovascular Events and Mortality: A Systematic Review and Meta‐Analysis
Saima Nisar, Asif Shah, Abida Perveen · 2026
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Description
Saima Nisar, Asif Shah, and Abida Perveen pool cohort studies on whether swings in uric acid over time forecast heart trouble. Their 2026 meta-analysis covers six cohorts with over one hundred sixty thousand adults. A single uric acid reading is standard, while repeated readings may say more.
Greater swing ties to a higher risk of death from all causes. The pooled hazard sits near one point one eight. Heart events show a similar lift, with a pooled hazard near one point two one. Heart death shows a pooled hazard near one point two five. One study adds a heart failure signal, with a hazard near one point three one. Sensitivity checks hold the pattern steady. Quality scores rate each cohort before pooling. The authors argue that tracking how uric acid moves, not just where it sits, sharpens risk reads for cardiovascular care.
Catalog record
| CREATOR | Saima Nisar, Asif Shah, Abida Perveen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |