Microbiome features associated with persistent intestinal carriages of Escherichia coli ST131 in a Southeast Asian cohort study
Adrian Low, Zhuoya Yang, Kylin Treruangrachada Anantaya, Siyan Zhao, Wei Cong Tan, Rebecca Lynn Perez, Hao Chung The, Shirmin Zhi Yan Lim, Lin Liu, Jean-Sebastien Gounot, Junmei Samantha Kwah, Rick Twee-Hee Ong, Niranjan Nagarajan, Jonathan Wei Jie Lee, Yin Mo · 2026
Read Microbiome features associated with persistent intestinal carriages of Escherichia coli ST131 in a Southeast Asian cohort study by Adrian Low, Zhuoya Yang, Kylin Treruangrachada Anantaya, Siyan Zhao, Wei Cong Tan, Rebecca Lynn Perez, Hao Chung The, Shirmin Zhi Yan Lim, Lin Liu, Jean-Sebastien Gounot, Junmei Samantha Kwah, Rick Twee-Hee Ong, Niranjan Nagarajan, Jonathan Wei Jie Lee, Yin Mo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13534727.txt.
Description
Low and colleagues report a 2026 study of gut bacteria in people who carry a harmful E. coli strain, ST131, in Southeast Asia. This strain can live in the gut silently and spread within households. The team used shotgun DNA reading of stool samples to compare persistent carriers, intermittent carriers, non-carriers, and their household contacts.
Carriage shifted the gut community's mix without lowering its overall diversity. Samples with ST131 had fewer helpful commensal species and less of one sugar-breakdown pathway. Persistent carriers showed the most disturbed communities, rich in pathobionts, meaning microbes that can turn harmful, and in pathways for iron capture and cell-wall building. Household comparisons flagged vitamin and sugar pathways that may sway who gets colonized. Knowing what gut states favor this strain could guide ways to clear it before it causes infection.
Catalog record
| CREATOR | Adrian Low, Zhuoya Yang, Kylin Treruangrachada Anantaya, Siyan Zhao, Wei Cong Tan, Rebecca Lynn Perez, Hao Chung The, Shirmin Zhi Yan Lim, Lin Liu, Jean-Sebastien Gounot, Junmei Samantha Kwah, Rick Twee-Hee Ong, Niranjan Nagarajan, Jonathan Wei Jie Lee, Yin Mo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 63 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |