Ovarian cancer tumor immune profiles associated with intrauterine device and oral contraceptive use
Jennifer M. Mongiovi, Ana Babic, Naoko Sasamoto, Mary K. Townsend, Allison F. Vitonis, Mollie Barnard, Jonathan Hecht, T. Rinda Soong, Jose R. Conejo-Garcia, Lauren C. Peres, Joellen M. Schildkraut, Holly R. Harris, Jennifer A. Doherty, Francesmary Modugno, Brooke L. Fridley, Shelley S. Tworoger, Kathryn L. Terry · 2026
Read Ovarian cancer tumor immune profiles associated with intrauterine device and oral contraceptive use by Jennifer M. Mongiovi, Ana Babic, Naoko Sasamoto, Mary K. Townsend, Allison F. Vitonis, Mollie Barnard, Jonathan Hecht, T. Rinda Soong, Jose R. Conejo-Garcia, Lauren C. Peres, Joellen M. Schildkraut, Holly R. Harris, Jennifer A. Doherty, Francesmary Modugno, Brooke L. Fridley, Shelley S. Tworoger, Kathryn L. Terry (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13534713.txt.
Description
Jennifer M Mongiovi and colleagues study in 2026 whether contraceptive history shapes immune cell patterns inside ovarian tumours. Non-hormonal devices create local inflammation in the uterus, while pills suppress ovulation, and both link to ovarian cancer risk in unlike ways. Tumour samples came from 24 tissue arrays across six studies.
High-grade serous tumours held the highest shares of T cells overall. Ever using a device linked modestly to more killer T cells in tumours, while pill use for a year or more linked to fewer. Device use also linked to more exhausted T cells in some subgroups.
Catalog record
| CREATOR | Jennifer M. Mongiovi, Ana Babic, Naoko Sasamoto, Mary K. Townsend, Allison F. Vitonis, Mollie Barnard, Jonathan Hecht, T. Rinda Soong, Jose R. Conejo-Garcia, Lauren C. Peres, Joellen M. Schildkraut, Holly R. Harris, Jennifer A. Doherty, Francesmary Modugno, Brooke L. Fridley, Shelley S. Tworoger, Kathryn L. Terry |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 72014 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |